Spruce Biosciences, Inc.

Quartel Adrian W bought 13,000 shares of SPRB on 27 July. They now own 13,000 SPRB shares.

Quartel Adrian W bought 0 shares of SPRB on 27 July. They now own 0 SPRB shares.

Szwarcberg Javier B. bought 266 shares of SPRB on 30 June. They now own 19,270 SPRB shares.

Barretto-Ko Percival bought 1,700 shares of SPRB on 21 May. They now own 1,700 SPRB shares.

Grey Michael G bought 1,700 shares of SPRB on 21 May. They now own 1,700 SPRB shares.

Spiegelman Daniel K bought 1,700 shares of SPRB on 21 May. They now own 1,700 SPRB shares.

Walbert Keli bought 1,700 shares of SPRB on 21 May. They now own 1,700 SPRB shares.

Simpson Camilla V bought 1,700 shares of SPRB on 21 May. They now own 1,700 SPRB shares.

Hooks Corwin Dale bought 11,000 shares of SPRB on 9 March. They now own 11,000 SPRB shares.

Hooks Corwin Dale bought 0 shares of SPRB on 9 March. They now own 0 SPRB shares.

Szwarcberg Javier B. bought 4,690 shares of SPRB on 31 December. They now own 19,004 SPRB shares.

Szwarcberg Javier B. sold 1,196 shares of SPRB on 15 December. They now own 2,392 SPRB shares.

Gharib Samir M. bought 496 shares of SPRB on 15 December. They now own 8,112 SPRB shares.

Szwarcberg Javier B. sold 1,480 shares of SPRB on 15 December. They now own 1,480 SPRB shares.

Gharib Samir M. sold 184 shares of SPRB on 15 December. They now own 8,263 SPRB shares.

Gharib Samir M. sold 496 shares of SPRB on 15 December. They now own 497 SPRB shares.

Szwarcberg Javier B. sold 608 shares of SPRB on 15 December. They now own 14,314 SPRB shares.

Szwarcberg Javier B. bought 1,480 shares of SPRB on 15 December. They now own 14,478 SPRB shares.

Gharib Samir M. bought 513 shares of SPRB on 15 December. They now own 8,447 SPRB shares.

Szwarcberg Javier B. sold 752 shares of SPRB on 15 December. They now own 13,726 SPRB shares.

Szwarcberg Javier B. bought 1,196 shares of SPRB on 15 December. They now own 14,922 SPRB shares.

Gharib Samir M. sold 178 shares of SPRB on 15 December. They now own 7,934 SPRB shares.

Gharib Samir M. sold 513 shares of SPRB on 15 December. They now own 1,027 SPRB shares.

Szwarcberg Javier B. bought 10,000 shares of SPRB on 11 December. They now own 10,000 SPRB shares.

Grey Michael G bought 1,255 shares of SPRB on 11 December. They now own 1,255 SPRB shares.

Simpson Camilla V bought 309 shares of SPRB on 11 December. They now own 309 SPRB shares.

Ways Douglas Kirk bought 400 shares of SPRB on 11 December. They now own 400 SPRB shares.

Gharib Samir M. sold 1,579 shares of SPRB on 11 December. They now own 0 SPRB shares.

Spiegelman Daniel K sold 88 shares of SPRB on 11 December. They now own 0 SPRB shares.

Spiegelman Daniel K bought 88 shares of SPRB on 11 December. They now own 88 SPRB shares.

Simpson Camilla V sold 309 shares of SPRB on 11 December. They now own 0 SPRB shares.

Grey Michael G bought 666 shares of SPRB on 11 December. They now own 666 SPRB shares.

Gharib Samir M. bought 7,600 shares of SPRB on 11 December. They now own 7,600 SPRB shares.

Szwarcberg Javier B. bought 4,950 shares of SPRB on 11 December. They now own 15,192 SPRB shares.

Gharib Samir M. sold 1,933 shares of SPRB on 11 December. They now own 0 SPRB shares.

Grey Michael G sold 400 shares of SPRB on 11 December. They now own 0 SPRB shares.

Grey Michael G bought 1,499 shares of SPRB on 11 December. They now own 1,499 SPRB shares.

Ways Douglas Kirk bought 1,250 shares of SPRB on 11 December. They now own 1,250 SPRB shares.

Gharib Samir M. bought 933 shares of SPRB on 11 December. They now own 933 SPRB shares.

Szwarcberg Javier B. sold 4,950 shares of SPRB on 11 December. They now own 14,850 SPRB shares.

Ways Douglas Kirk sold 266 shares of SPRB on 11 December. They now own 0 SPRB shares.

Gharib Samir M. bought 733 shares of SPRB on 11 December. They now own 733 SPRB shares.

Gharib Samir M. sold 733 shares of SPRB on 11 December. They now own 0 SPRB shares.

Spiegelman Daniel K bought 458 shares of SPRB on 11 December. They now own 458 SPRB shares.

Gharib Samir M. bought 1,933 shares of SPRB on 11 December. They now own 1,933 SPRB shares.

Gharib Samir M. bought 953 shares of SPRB on 11 December. They now own 953 SPRB shares.

Simpson Camilla V bought 400 shares of SPRB on 11 December. They now own 400 SPRB shares.

Grey Michael G sold 387 shares of SPRB on 11 December. They now own 0 SPRB shares.

Gharib Samir M. bought 1,579 shares of SPRB on 11 December. They now own 1,579 SPRB shares.

Barretto-Ko Percival sold 800 shares of SPRB on 11 December. They now own 0 SPRB shares.

Simpson Camilla V bought 173 shares of SPRB on 11 December. They now own 173 SPRB shares.

Spiegelman Daniel K bought 400 shares of SPRB on 11 December. They now own 400 SPRB shares.

Simpson Camilla V sold 362 shares of SPRB on 11 December. They now own 0 SPRB shares.

Grey Michael G sold 133 shares of SPRB on 11 December. They now own 0 SPRB shares.

Barretto-Ko Percival bought 800 shares of SPRB on 11 December. They now own 800 SPRB shares.

Gharib Samir M. sold 680 shares of SPRB on 11 December. They now own 7,616 SPRB shares.

Gharib Samir M. sold 933 shares of SPRB on 11 December. They now own 0 SPRB shares.

Grey Michael G sold 666 shares of SPRB on 11 December. They now own 0 SPRB shares.

Szwarcberg Javier B. sold 10,000 shares of SPRB on 11 December. They now own 0 SPRB shares.

Simpson Camilla V bought 362 shares of SPRB on 11 December. They now own 362 SPRB shares.

Gharib Samir M. bought 1,900 shares of SPRB on 11 December. They now own 8,296 SPRB shares.

Spiegelman Daniel K sold 400 shares of SPRB on 11 December. They now own 0 SPRB shares.

Simpson Camilla V sold 400 shares of SPRB on 11 December. They now own 0 SPRB shares.

Ways Douglas Kirk bought 266 shares of SPRB on 11 December. They now own 266 SPRB shares.

Ways Douglas Kirk sold 1,250 shares of SPRB on 11 December. They now own 3,750 SPRB shares.

Grey Michael G sold 1,499 shares of SPRB on 11 December. They now own 0 SPRB shares.

Spiegelman Daniel K sold 458 shares of SPRB on 11 December. They now own 0 SPRB shares.

Grey Michael G bought 133 shares of SPRB on 11 December. They now own 133 SPRB shares.

Szwarcberg Javier B. bought 1,666 shares of SPRB on 11 December. They now own 1,666 SPRB shares.

Walbert Keli bought 0 shares of SPRB on 11 December. They now own 0 SPRB shares.

Gharib Samir M. sold 953 shares of SPRB on 11 December. They now own 0 SPRB shares.

Simpson Camilla V sold 133 shares of SPRB on 11 December. They now own 0 SPRB shares.

Simpson Camilla V sold 173 shares of SPRB on 11 December. They now own 0 SPRB shares.

Grey Michael G sold 1,255 shares of SPRB on 11 December. They now own 0 SPRB shares.

Ways Douglas Kirk bought 5,000 shares of SPRB on 11 December. They now own 5,000 SPRB shares.

Szwarcberg Javier B. bought 19,800 shares of SPRB on 11 December. They now own 19,800 SPRB shares.

Gharib Samir M. sold 1,900 shares of SPRB on 11 December. They now own 5,700 SPRB shares.

Szwarcberg Javier B. sold 2,194 shares of SPRB on 11 December. They now own 12,998 SPRB shares.

Grey Michael G bought 387 shares of SPRB on 11 December. They now own 387 SPRB shares.

Walbert Keli bought 3,400 shares of SPRB on 11 December. They now own 3,400 SPRB shares.

Ways Douglas Kirk sold 400 shares of SPRB on 11 December. They now own 0 SPRB shares.

Simpson Camilla V bought 133 shares of SPRB on 11 December. They now own 133 SPRB shares.

Grey Michael G bought 400 shares of SPRB on 11 December. They now own 400 SPRB shares.

Gharib Samir M. sold 184 shares of SPRB on 10 December. They now own 6,396 SPRB shares.

Gharib Samir M. sold 514 shares of SPRB on 10 December. They now own 1,539 SPRB shares.

Gharib Samir M. bought 514 shares of SPRB on 10 December. They now own 6,580 SPRB shares.

Szwarcberg Javier B. bought 1,196 shares of SPRB on 10 December. They now own 10,670 SPRB shares.

Szwarcberg Javier B. sold 428 shares of SPRB on 10 December. They now own 10,242 SPRB shares.

Szwarcberg Javier B. sold 1,196 shares of SPRB on 10 December. They now own 3,588 SPRB shares.

Gharib Samir M. sold 661 shares of SPRB on 20 October. They now own 6,066 SPRB shares.

Gharib Samir M. bought 2,053 shares of SPRB on 20 October. They now own 6,727 SPRB shares.

Gharib Samir M. bought 2,053 shares of SPRB on 20 October. They now own 2,053 SPRB shares.

Szwarcberg Javier B. bought 4,784 shares of SPRB on 20 October. They now own 11,013 SPRB shares.

Gharib Samir M. sold 2,053 shares of SPRB on 20 October. They now own 0 SPRB shares.

Szwarcberg Javier B. sold 1,539 shares of SPRB on 20 October. They now own 9,474 SPRB shares.

Szwarcberg Javier B. sold 4,784 shares of SPRB on 20 October. They now own 0 SPRB shares.

Szwarcberg Javier B. bought 4,784 shares of SPRB on 20 October. They now own 4,784 SPRB shares.

Parkman Healthcare Partners Llc bought 0 shares of SPRB on 6 October. They now own 1,051 SPRB shares.

Parkman Healthcare Partners Llc bought 256 shares of SPRB on 6 October. They now own 1,307 SPRB shares.

Parkman Healthcare Partners Llc sold 232 shares of SPRB on 6 October. They now own 1,075 SPRB shares.

Parkman Healthcare Partners Llc sold 25 shares of SPRB on 6 October. They now own 1,050 SPRB shares.

Ways Kirk bought 30,000 shares of SPRB on 23 July. They now own 30,000 SPRB shares.

Aynechi Tiba bought 30,000 shares of SPRB on 22 July. They now own 30,000 SPRB shares.

Grey Michael G bought 30,000 shares of SPRB on 22 July. They now own 30,000 SPRB shares.

Barretto-Ko Percival bought 30,000 shares of SPRB on 22 July. They now own 30,000 SPRB shares.

Muralidhar Bali bought 30,000 shares of SPRB on 22 July. They now own 30,000 SPRB shares.

Spiegelman Daniel K bought 30,000 shares of SPRB on 22 July. They now own 30,000 SPRB shares.

Simpson Camilla V bought 30,000 shares of SPRB on 22 July. They now own 30,000 SPRB shares.

Szwarcberg Javier B. sold 111,000 shares of SPRB on 16 December. They now own 222,000 SPRB shares.

Charlton Ralph William Iii sold 31,750 shares of SPRB on 16 December. They now own 63,500 SPRB shares.

Charlton Ralph William Iii sold 9,491 shares of SPRB on 16 December. They now own 140,918 SPRB shares.

Charlton Ralph William Iii sold 11,329 shares of SPRB on 16 December. They now own 161,339 SPRB shares.

Gharib Samir M. bought 38,500 shares of SPRB on 16 December. They now own 340,328 SPRB shares.

Gharib Samir M. sold 37,250 shares of SPRB on 16 December. They now own 74,500 SPRB shares.

Gharib Samir M. sold 38,500 shares of SPRB on 16 December. They now own 115,500 SPRB shares.

Gharib Samir M. bought 37,250 shares of SPRB on 16 December. They now own 363,841 SPRB shares.

Charlton Ralph William Iii bought 26,600 shares of SPRB on 16 December. They now own 150,409 SPRB shares.

Gharib Samir M. sold 13,737 shares of SPRB on 16 December. They now own 326,591 SPRB shares.

Gharib Samir M. sold 13,291 shares of SPRB on 16 December. They now own 350,550 SPRB shares.

Szwarcberg Javier B. bought 89,700 shares of SPRB on 16 December. They now own 427,801 SPRB shares.

Szwarcberg Javier B. sold 89,700 shares of SPRB on 16 December. They now own 269,100 SPRB shares.

Szwarcberg Javier B. sold 32,005 shares of SPRB on 16 December. They now own 395,796 SPRB shares.

Szwarcberg Javier B. sold 39,605 shares of SPRB on 16 December. They now own 467,191 SPRB shares.

Charlton Ralph William Iii sold 26,600 shares of SPRB on 16 December. They now own 79,800 SPRB shares.

Charlton Ralph William Iii bought 31,750 shares of SPRB on 16 December. They now own 172,668 SPRB shares.

Szwarcberg Javier B. bought 111,000 shares of SPRB on 16 December. They now own 506,796 SPRB shares.

Szwarcberg Javier B. sold 358,800 shares of SPRB on 10 December. They now own 358,800 SPRB shares.

Szwarcberg Javier B. sold 128,020 shares of SPRB on 10 December. They now own 338,101 SPRB shares.

Gharib Samir M. sold 54,948 shares of SPRB on 10 December. They now own 301,828 SPRB shares.

Charlton Ralph William Iii sold 106,400 shares of SPRB on 10 December. They now own 106,400 SPRB shares.

Gharib Samir M. bought 154,000 shares of SPRB on 10 December. They now own 356,776 SPRB shares.

Szwarcberg Javier B. bought 358,800 shares of SPRB on 10 December. They now own 466,121 SPRB shares.

Gharib Samir M. sold 154,000 shares of SPRB on 10 December. They now own 154,000 SPRB shares.

Charlton Ralph William Iii bought 106,400 shares of SPRB on 10 December. They now own 161,773 SPRB shares.

Charlton Ralph William Iii sold 37,964 shares of SPRB on 10 December. They now own 123,809 SPRB shares.

Barretto-Ko Percival bought 30,000 shares of SPRB on 22 May. They now own 30,000 SPRB shares.

Spiegelman Daniel K bought 30,000 shares of SPRB on 22 May. They now own 30,000 SPRB shares.

Ways Kirk bought 30,000 shares of SPRB on 22 May. They now own 30,000 SPRB shares.

Simpson Camilla V bought 30,000 shares of SPRB on 22 May. They now own 30,000 SPRB shares.

Aynechi Tiba bought 30,000 shares of SPRB on 22 May. They now own 30,000 SPRB shares.

Grey Michael G bought 30,000 shares of SPRB on 22 May. They now own 30,000 SPRB shares.

Muralidhar Bali bought 30,000 shares of SPRB on 22 May. They now own 30,000 SPRB shares.

Novo Holdings A/S sold 465,021 shares of SPRB on 21 March. They now own 2,550,000 SPRB shares.

Novo Holdings A/S sold 359,979 shares of SPRB on 20 March. They now own 3,015,021 SPRB shares.

Novo Holdings A/S sold 593,000 shares of SPRB on 19 March. They now own 3,375,000 SPRB shares.

Novo Holdings A/S sold 842,020 shares of SPRB on 18 March. They now own 3,968,000 SPRB shares.

Gharib Samir M. bought 154,000 shares of SPRB on 14 March. They now own 154,000 SPRB shares.

Charlton Ralph William Iii bought 106,400 shares of SPRB on 14 March. They now own 106,400 SPRB shares.

Novo Holdings A/S sold 1,912,316 shares of SPRB on 14 March. They now own 4,810,020 SPRB shares.

Szwarcberg Javier B. bought 358,800 shares of SPRB on 14 March. They now own 358,800 SPRB shares.

Gharib Samir M. bought 11,255 shares of SPRB on 29 December. They now own 202,776 SPRB shares.

Charlton Ralph William Iii bought 9,361 shares of SPRB on 29 December. They now own 55,373 SPRB shares.

Gharib Samir M. sold 37,250 shares of SPRB on 15 December. They now own 111,750 SPRB shares.

Gharib Samir M. bought 75,000 shares of SPRB on 15 December. They now own 190,366 SPRB shares.

Charlton Ralph William Iii sold 10,980 shares of SPRB on 15 December. They now own 46,012 SPRB shares.

Szwarcberg Javier B. bought 111,000 shares of SPRB on 15 December. They now own 145,705 SPRB shares.

Charlton Ralph William Iii bought 31,750 shares of SPRB on 15 December. They now own 56,992 SPRB shares.

Gharib Samir M. sold 23,213 shares of SPRB on 15 December. They now own 167,153 SPRB shares.

Szwarcberg Javier B. sold 111,000 shares of SPRB on 15 December. They now own 333,000 SPRB shares.

Gharib Samir M. bought 37,250 shares of SPRB on 15 December. They now own 204,403 SPRB shares.

Szwarcberg Javier B. sold 38,384 shares of SPRB on 15 December. They now own 107,321 SPRB shares.

Gharib Samir M. sold 75,000 shares of SPRB on 15 December. They now own 75,000 SPRB shares.

Charlton Ralph William Iii sold 31,750 shares of SPRB on 15 December. They now own 95,250 SPRB shares.

Gharib Samir M. sold 12,882 shares of SPRB on 15 December. They now own 191,521 SPRB shares.

Gharib Samir M. bought 308,000 shares of SPRB on 14 December. They now own 308,000 SPRB shares.

Szwarcberg Javier B. bought 717,600 shares of SPRB on 14 December. They now own 717,600 SPRB shares.

Charlton Ralph William Iii bought 212,800 shares of SPRB on 14 December. They now own 212,800 SPRB shares.

Szwarcberg Javier B. bought 125,000 shares of SPRB on 26 November. They now own 125,000 SPRB shares.

Gharib Samir M. bought 75,000 shares of SPRB on 8 November. They now own 75,000 SPRB shares.

Gharib Samir M. bought 10,484 shares of SPRB on 30 June. They now own 66,302 SPRB shares.

Charlton Ralph William Iii bought 12,378 shares of SPRB on 30 June. They now own 25,242 SPRB shares.

Szwarcberg Javier B. bought 20,000 shares of SPRB on 30 June. They now own 34,705 SPRB shares.

Gharib Samir M. bought 75,000 shares of SPRB on 30 June. They now own 141,302 SPRB shares.

Gharib Samir M. sold 25,936 shares of SPRB on 30 June. They now own 115,366 SPRB shares.

Gharib Samir M. sold 75,000 shares of SPRB on 30 June. They now own 150,000 SPRB shares.

Spiegelman Daniel K bought 30,000 shares of SPRB on 25 May. They now own 30,000 SPRB shares.

Simpson Camilla V bought 30,000 shares of SPRB on 25 May. They now own 30,000 SPRB shares.

Muralidhar Bali bought 30,000 shares of SPRB on 25 May. They now own 30,000 SPRB shares.

Barretto-Ko Percival sold 0 shares of SPRB on 25 May. They now own 0 SPRB shares.

O'Donnell Niall bought 30,000 shares of SPRB on 25 May. They now own 30,000 SPRB shares.

Barretto-Ko Percival bought 60,000 shares of SPRB on 25 May. They now own 60,000 SPRB shares.

Grey Michael G bought 30,000 shares of SPRB on 25 May. They now own 30,000 SPRB shares.

Aynechi Tiba bought 30,000 shares of SPRB on 25 May. They now own 30,000 SPRB shares.

Ways Kirk bought 30,000 shares of SPRB on 25 May. They now own 30,000 SPRB shares.

O'Donnell Niall bought 630,400 shares of SPRB on 16 February. They now own 1,326,305 SPRB shares.

O'Donnell Niall bought 472,800 shares of SPRB on 16 February. They now own 472,800 SPRB shares.

Novo Holdings A/S bought 2,208,000 shares of SPRB on 16 February. They now own 6,722,336 SPRB shares.

Novo Holdings A/S bought 1,656,000 shares of SPRB on 16 February. They now own 1,656,000 SPRB shares.

Gharib Samir M. sold 15,293 shares of SPRB on 3 January. They now own 55,818 SPRB shares.

Gharib Samir M. bought 37,500 shares of SPRB on 3 January. They now own 71,111 SPRB shares.

Gharib Samir M. sold 37,500 shares of SPRB on 3 January. They now own 225,000 SPRB shares.

Charlton Ralph William Iii bought 12,864 shares of SPRB on 30 December. They now own 12,864 SPRB shares.

Gharib Samir M. bought 1 shares of SPRB on 30 December. They now own 33,611 SPRB shares.

Szwarcberg Javier B. bought 14,705 shares of SPRB on 30 December. They now own 14,705 SPRB shares.

Szwarcberg Javier B. bought 444,000 shares of SPRB on 5 December. They now own 444,000 SPRB shares.

Charlton Ralph William Iii bought 127,000 shares of SPRB on 5 December. They now own 127,000 SPRB shares.

Gharib Samir M. bought 149,000 shares of SPRB on 5 December. They now own 149,000 SPRB shares.

Gharib Samir M. sold 37,500 shares of SPRB on 30 June. They now own 262,500 SPRB shares.

Gharib Samir M. bought 37,500 shares of SPRB on 30 June. They now own 41,132 SPRB shares.

Gharib Samir M. bought 5,446 shares of SPRB on 30 June. They now own 46,578 SPRB shares.